Diffuse retinopathy following measles, mumps, and rubella vaccination

Blindness due to optic neuritis or panretinopathy has been reported as an acute complication of natural measles infection.5 Recently, loss of visual acuity following measles, mumps, and rubella (MMR) vaccination with the fundoscopic changes of optic neuritis has been described.6 We have observed a c...

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Bibliographic Details
Published in:Pediatrics (Evanston) 1985-12, Vol.76 (6), p.989-991
Main Authors: MARSHALL, G. S, WRIGHT, P. F, FENICHEL, G. M, KARZON, D. T
Format: Article
Language:English
Subjects:
Biological and medical sciences
Blindness - chemically induced
Blindness - physiopathology
Female
Humans
Infant
Measles Vaccine - adverse effects
Medical sciences
Mumps Vaccine - adverse effects
Ophthalmology
Retinitis - chemically induced
Retinitis - physiopathology
Retinopathies
Rubella Vaccine - adverse effects
Visual Acuity
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Summary:Blindness due to optic neuritis or panretinopathy has been reported as an acute complication of natural measles infection.5 Recently, loss of visual acuity following measles, mumps, and rubella (MMR) vaccination with the fundoscopic changes of optic neuritis has been described.6 We have observed a child with blindness due to diffuse neuroretinitis temporally associated with measles, mumps, and rubella vaccination and the development of a postvaccination measles syndrome. CASE REPORT A 16-month-old baby girl presented with acute loss of vision 16 days after routine measles, mumps, and rubella vaccination. The infant had been previously healthy and developmentally normal. She had received three previous oral polio and diphtheria, tetanus, and pertussis vaccinations without adverse reactions.
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.76.6.989