Surface-induced dissociation in tandem quadrupole mass spectrometers: A comparison of three designs

• Published in: Journal of the American Society for Mass Spectrometry 1992, Vol.3 (1), p.27-32
• Main Authors: Wysocki, Vicki H., Ding, Jian-Mei, Jones, Jennifer L., Callahan, John H., King, Fred L.
• Format: Article
• Language: English
• Subjects: Exact sciences and technology; Instruments, apparatus, components and techniques common to several branches of physics and astronomy; Mass spectrometers and related techniques; Physics
• ISSN: 1044-0305; 1879-1123
• DOI: 10.1016/1044-0305(92)85015-C

Three different devices that can be used for surface-induced dissociation (SID) in tandem quadrupole instruments are compared here. The designs were compared by examining the fragmentation of several compounds including benzene, W(CO) 6, and (CH) 3 4N +. These studies show that SID can be readily implemented on a variety of tandem quadrupole instruments and that the spectra obtained with the in-line and 90° instruments are similar Evidence is presented that confirms that high average internal energies and narrow distributions of internal energy are available by this technique. Efficiencies for fragmentation of odd-electron ions are on the order of those previously reported by others. The overall SID efficiency for even-electron ions is higher than that for odd-electron ions of similar structure.