Evaluating the Accuracy of the Visual Field Index for the Humphrey Visual Field Analyzer in Patients with Mild to Moderate Glaucoma

• Published in: American journal of ophthalmology 2013-12, Vol.156 (6), p.1272-1276
• Main Authors: Talbot, Renée, Goldberg, Ivan, Kelly, Patrick
• Format: Article
• Language: English
• Subjects: Accuracy; Algorithms; Cohort Studies; Confidence intervals; False Positive Reactions; Female; Follow-Up Studies; Glaucoma; Glaucoma - diagnosis; Humans; Intraocular Pressure; Lasers; Male; Middle Aged; Ophthalmology; Predictive Value of Tests; Reproducibility of Results; Retrospective Studies; Software; Studies; Therapy; Values; Vision Disorders - diagnosis; Visual Acuity - physiology; Visual aids; Visual Field Tests - standards; Visual Fields
• ISSN: 0002-9394; 1879-1891
• DOI: 10.1016/j.ajo.2013.07.025

Purpose To evaluate the accuracy of the visual field index (VFI) for the Humphrey Visual Field Analyzer in a population of patients with mild to moderate glaucoma. Design Retrospective cohort study. Methods The study included 42 patients (61 eyes) with at least 11 years of follow-up, and annual automated visual fields (VFs). Patients with mean deviations ≤−20 dB were excluded. All unreliable fields were omitted (fixation losses ≥20%, false-positive ≥15%, false-negative ≥33%). The VFs were divided into two 5-year series and the data were analyzed by the new Humphrey Visual Field Analyzer software. Projected VFIs from the first 5 years were compared with observed values obtained from the last 5 years. Unreliable fields initially excluded were reintroduced into the series (22 eyes) to create a comparison. Results Predicted VFIs were accurate with a mean overestimation of VF deterioration of 1.37% (95% CI: −0.22%, 2.96%). Of the predicted values, 95% were between −4.5% and 5.2% of the observed values when the predicted VFI was ≥90%; and between −13.8% and 20.5% when the predicted VFI was