Relationship between long-term exposure to low-level arsenic in drinking water and the prevalence of abnormal blood pressure

► We focused on the impact of long-term exposure to low-level arsenic in drinking water on blood pressure, pulse pressure (PP) and arterial blood pressure (MAP). ► The prevalence of hypertension and abnormal pulse pressure (PP) and arterial blood pressure (MAP) is marked among a long-term and low-le...

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Bibliographic Details
Published in:Journal of hazardous materials 2013-11, Vol.262, p.1154-1158
Main Authors: Zhang, Chuanwu, Mao, Guangyun, He, Suxia, Yang, Zuopeng, Yang, Wei, Zhang, Xiaojing, Qiu, Wenting, Ta, Na, Cao, Li, Yang, Hui, Guo, Xiaojuan
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Alcohol Drinking
Arsenic
Arsenic - analysis
Arsenic - toxicity
Blood Pressure
Body Mass Index
Cross-Sectional Studies
Cross-sectional study
Drinking Water
Environmental Exposure
Female
Humans
Hypertension - diagnosis
Hypertension - epidemiology
Inner Mongolia
Male
Middle Aged
Mongolia - epidemiology
Multivariate Analysis
Odds Ratio
Water Pollutants, Chemical - toxicity
Water Supply
Young Adult
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Summary:► We focused on the impact of long-term exposure to low-level arsenic in drinking water on blood pressure, pulse pressure (PP) and arterial blood pressure (MAP). ► The prevalence of hypertension and abnormal pulse pressure (PP) and arterial blood pressure (MAP) is marked among a long-term and low-level arsenic exposure population. ► The prevalence of hypertension and abnormal pulse pressure (PP) as well as arterial blood pressure (MAP) significantly increases with the duration of arsenic exposure. Arsenic increases the risk and incidence of cardiovascular disease. To explore the impact of long-term exposure to low-level arsenic in drinking water on blood pressure including pulse pressure (PP) and mean arterial blood pressure (MAP), a cross-sectional study was conducted in 2010 in which the blood pressure of 405 villagers was measured, who had been drinking water with an inorganic arsenic content 30–50 years of arsenic exposure and a 2.95-fold (95%CI: 1.31–6.67) increase in the group with >50 years exposure. Furthermore, the odds ratio for prevalence of abnormal PP and MAP were 1.06 (95%CI: 0.24–4.66) and 0.87 (95%CI: 0.36–2.14) in the group with >30–50 years of exposure, and were 2.46 (95%CI: 0.87–6.97) and 3.75 (95%CI: 1.61–8.71) for the group with >50 years exposure, compared to the group with arsenic exposure ≤30 years respectively. Significant trends for Hypertension (p
ISSN:0304-3894
1873-3336
DOI:10.1016/j.jhazmat.2012.09.045