A new pentacyclic triterpenoid from the leaves of Lantana montevidensis (Spreng.) Briq

A new pentacyclic triterpenoid, 3β,25-epoxy-3α,22β,23α-trihydroxy-olean-12-en-28-oic acid (1), together with seven known compounds, including five triterpenoids, β-amyrin (2), lantadene B (3), lantanilic acid (4), lantanolic acid (5) and ursolic acid (6) in addition to β-sitosterol (7) and benzoic a...

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Bibliographic Details
Published in:Natural product research 2013-11, Vol.27 (21), p.2046-2052
Main Authors: Makboul, Makboul A., Attia, Ahmed A., Farag, Salwa F., Mohamed, Nesma M., Ross, Samir A., Takaya, Yoshiaki, Niwa, Masatake
Format: Article
Language:English
Subjects:
antibacterial activity
Lantana - chemistry
Lantana montevidensis
pentacyclic triterpenoid
Plant Leaves - chemistry
Triterpenes - chemistry
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Summary:A new pentacyclic triterpenoid, 3β,25-epoxy-3α,22β,23α-trihydroxy-olean-12-en-28-oic acid (1), together with seven known compounds, including five triterpenoids, β-amyrin (2), lantadene B (3), lantanilic acid (4), lantanolic acid (5) and ursolic acid (6) in addition to β-sitosterol (7) and benzoic acid (8) has been isolated from the leaves of Lantana montevidensis. Their chemical structures were elucidated by spectroscopic analysis and by comparison with the literature data and/or authentic samples. Compound 1 showed moderate to weak antibacterial activity against Staphylococcus aureus and Escherichia coli.
ISSN:1478-6419
1478-6427
DOI:10.1080/14786419.2013.824443