Porcine model of intracoronary pulverization of stent struts by rotablation atherectomy

Objective To evaluate the feasibility and safety of rotablation atherectomy in a suboptimally expanded stent. Methods Seven pigs underwent suboptimal stent expansion in the left anterior descending coronary. Pulverization of the stent struts was performed by rotablation atherectomy with two differen...

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Published in:Catheterization and cardiovascular interventions 2013-12, Vol.82 (7), p.E842-E848
Main Authors: Quang, Thuy Tran, Hatem, Raja, Rousseau, Guy, Dube, Bruno, Samson, Caroline, Schampaert, Erick, Charron, Thierry
Format: Article
Language:English
Subjects:
Angioplasty, Balloon, Coronary - adverse effects
Angioplasty, Balloon, Coronary - instrumentation
Animals
Atherectomy, Coronary - adverse effects
Coronary Angiography
Coronary Vasospasm - diagnosis
Coronary Vasospasm - etiology
Coronary Vessels - diagnostic imaging
Device Removal - adverse effects
Device Removal - methods
distal embolization
Feasibility Studies
Male
Metals
Models, Animal
Prosthesis Design
Prosthesis Failure
Risk Factors
rotablator
stent
Stents
Swine
Time Factors
Ultrasonography, Interventional
vascular bed
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Summary:Objective To evaluate the feasibility and safety of rotablation atherectomy in a suboptimally expanded stent. Methods Seven pigs underwent suboptimal stent expansion in the left anterior descending coronary. Pulverization of the stent struts was performed by rotablation atherectomy with two different burr sizes. Two types of control porcine models were used: pigs with fully expanded stents and pigs without stents. Continuous electrocardiogram readings as well as microscopic and radiologic analysis of cardiac tissue were performed. Results Rotablation atherectomy reduces the suboptimally expanded stent by (26.95 ± 5.03)%. Ninety‐five percent of the metal microparticles, imbedded in the suboptimally expanded stent group cardiac tissue, are less than 15 μm. Transient vasospasm and ST segments elevations were observed during rotablation atherectomy, which returned to basal conditions at the end of the intervention. Conclusion Our study demonstrated the feasibility and safety of using rotablation atherectomy to pulverize stent struts in a suboptimally expanded stent. © 2012 Wiley Periodicals, Inc.
ISSN:1522-1946
1522-726X
DOI:10.1002/ccd.24650