The Electrophoretical Determination of Serum Protein Fractions in Lycopene Treated Experimental Diabetic Rats

This study was planned to determine the effects of lycopene treatment on serum protein fractions in experimental diabetic rats. In order to induce diabetes in rats in the diabetes (D) and diabetes + lycopene (DL) groups, rats were given 45 mg/kg single-dose streptozotocin intraperitoneally. Lycopene...

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Bibliographic Details
Published in:Cell biochemistry and biophysics 2013-12, Vol.67 (3), p.1283-1289
Main Authors: Yuksek, Veysel, Dede, Semiha, Ceylan, Ebubekir
Format: Article
Language:English
Subjects:
Animals
Antioxidants - therapeutic use
Biochemistry
Biological and Medical Physics
Biomedical and Life Sciences
Biophysics
Biotechnology
Blood Glucose - metabolism
Blood Proteins - chemistry
Blood Proteins - metabolism
Carotenoids - therapeutic use
Cell Biology
Diabetes Mellitus, Experimental - drug therapy
Electrophoresis, Agar Gel
gamma-Globulins - chemistry
gamma-Globulins - metabolism
Glycated Hemoglobin A - metabolism
Life Sciences
Male
Original Paper
Pharmacology/Toxicology
Rats
Rats, Wistar
Serum Albumin - chemistry
Serum Albumin - metabolism
Sunflower oil
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Summary:This study was planned to determine the effects of lycopene treatment on serum protein fractions in experimental diabetic rats. In order to induce diabetes in rats in the diabetes (D) and diabetes + lycopene (DL) groups, rats were given 45 mg/kg single-dose streptozotocin intraperitoneally. Lycopene (10 mg/kg/day dissolved in sunflower oil) was administered to the rats in the lycopene-only (L) and DL groups. Blood glucose levels and HbA1c% in DL group and diabetes group increased ( p  
ISSN:1085-9195
1559-0283
DOI:10.1007/s12013-013-9660-2