Comparison of the Therapeutic Effectiveness of Sustained Low-Efficiency Dialysis (SLED) with Continuous Blood Purification (CBP) in Critically Ill Patients

The differences in therapeutic effectiveness between sustained low-efficiency dialysis (SLED) and continuous blood purification (CBP) were investigated. In order to assess the different treatment methods, 56 critically ill patients were divided into two groups, the CBP group and the SLED group. A co...

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Bibliographic Details
Published in:Cell biochemistry and biophysics 2013-12, Vol.67 (3), p.923-927
Main Authors: Cheng, Junzhang, Hu, Shouliang, Lu, Hongzhu, Lei, Qingfeng, Liu, Juncheng, Yuan, Fanli, Chen, Rong
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Alanine Transaminase - blood
APACHE
Aspartate Aminotransferases - blood
Biochemistry
Biological and Medical Physics
Biomedical and Life Sciences
Biophysics
Biotechnology
Blood
Cell Biology
Creatine Kinase - blood
Creatine Kinase, MB Form - blood
Creatinine - blood
Critical Illness - mortality
Critical Illness - therapy
Dialysis
Female
Hemodynamics
Humans
Length of Stay
Life Sciences
Male
Middle Aged
Mortality
Original Paper
Pharmacology/Toxicology
Renal Dialysis - methods
Renal Dialysis - standards
Sex Factors
Survival
Survival Rate
Treatment Outcome
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Summary:The differences in therapeutic effectiveness between sustained low-efficiency dialysis (SLED) and continuous blood purification (CBP) were investigated. In order to assess the different treatment methods, 56 critically ill patients were divided into two groups, the CBP group and the SLED group. A comparison was made between all the biochemical indicators, in-hospital duration, hemodynamic parameters, acute physiology and chronic health evaluation (APACHE-II), the survival, and the mortality rates. After treatment, the levels of serum creatine kinase isozyme MB (CK-MB), creatine kinase, creatinine, glutamate-oxalacetate transaminase (AST), glutamate-pyruvate transaminase (ALT), APACHE II score on the 1st, 2nd, and 7th day in both the treatment groups were lower than that before the treatment ( P   0.05). It was concluded that SLED has similar hemodynamic stability with CBP and the two methods have similar treatment effects in critically ill patients. However, we noticed that SLED can be relatively economical and convenient for critically ill patients in clinical practice.
ISSN:1085-9195
1559-0283
DOI:10.1007/s12013-013-9583-y