Usefulness of Combined Risk Stratification With Heart Rate and Systolic Blood Pressure in the Management of Chronic Heart Failure: A Report From the CHART-2 Study

Background: The appropriate target ranges of heart rate (HR) and systolic blood pressure (SBP) for the management of chronic heart failure (CHF) patients remain to be elucidated in a large-scale cohort study. Methods and Results: We examined 3,029 consecutive CHF patients with sinus rhythm (SR) (mea...

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Bibliographic Details
Published in:Circulation Journal 2013, Vol.77(12), pp.2954-2962
Main Authors: Miura, Masanobu, Sakata, Yasuhiko, Miyata, Satoshi, Nochioka, Kotaro, Takada, Tsuyoshi, Tadaki, Soichiro, Takahashi, Jun, Shiba, Nobuyuki, Shimokawa, Hiroaki, on behalf of the CHART-2 Investigators
Format: Article
Language:English
Subjects:
Aged
Blood Pressure
CHART-2
Chronic Disease
Chronic heart failure
Female
Follow-Up Studies
Heart Failure - mortality
Heart Failure - physiopathology
Heart Rate
Humans
Male
Middle Aged
Prognosis
Risk Factors
Survival Rate
Systolic blood pressure
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Summary:Background: The appropriate target ranges of heart rate (HR) and systolic blood pressure (SBP) for the management of chronic heart failure (CHF) patients remain to be elucidated in a large-scale cohort study. Methods and Results: We examined 3,029 consecutive CHF patients with sinus rhythm (SR) (mean age, 67.9 years) registered in the Chronic Heart Failure Analysis and Registry in the Tohoku District-2 Study (CHART-2; NCT00418041). There were 357 deaths (11.8%) during the median follow-up of 3.1 years. We first performed the classification and regression tree analysis for mortality, identifying SBP 70beats/min and SBP 115mmHg and HR
ISSN:1346-9843
1347-4820
DOI:10.1253/circj.CJ-13-0725