Is it true remission? A study of remitted patients affected by schizophrenia and schizoaffective disorders

Abstract To date, few studies have reported analytical data relating to clinical remission, functional remission and subjective experience. The present study aimed to investigate these aspects in a sample of chronic outpatients. Methods: 112 schizophrenic or schizoaffective outpatients (Males=60; Fe...

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Bibliographic Details
Published in:Psychiatry research 2013-12, Vol.210 (3), p.739-744
Main Authors: Pinna, Federica, Deriu, Luca, Lepori, Tiziana, Maccioni, Raffaela, Milia, Paola, Sarritzu, Elisabetta, Tusconi, Massimo, Carpiniello, Bernardo
Format: Article
Language:English
Subjects:
Adult
Adult and adolescent clinical studies
Antipsychotic Agents - therapeutic use
Biological and medical sciences
Female
Functioning
Humans
Male
Medical sciences
Middle Aged
Outpatients
Personal Satisfaction
Prospective Studies
Psychiatric Status Rating Scales - statistics & numerical data
Psychiatry
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychoses
Psychotic Disorders - drug therapy
Psychotic Disorders - psychology
Psychotic Disorders - rehabilitation
Quality of life
Quality of Life - psychology
Remission
Remission Induction
Schizoaffective disorders
Schizophrenia
Schizophrenia - drug therapy
Schizophrenia - rehabilitation
Schizophrenic Psychology
Severity of Illness Index
Subjective well-being
Surveys and Questionnaires
Symptomatology
Treatment Outcome
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Summary:Abstract To date, few studies have reported analytical data relating to clinical remission, functional remission and subjective experience. The present study aimed to investigate these aspects in a sample of chronic outpatients. Methods: 112 schizophrenic or schizoaffective outpatients (Males=60; Females=52; mean age 43.5±9.42 yr) were evaluated with regard to symptomatology (SCID-I; PANSS, CGI-SCH scales), functioning (PSP scale), subjective wellbeing (SWN-K scale) and Quality of Life (WHO-QoL-Bref scale). Results: 50% of patients were found to be in remission. Significantly higher scores at PANNS, CGI-SCH, PSP, but not at SWN and WHO-QoL, were found among remitted patients; a relevant proportion of remitted subjects continued to manifest a moderate level of symptoms (score >3) both at PANSS (35% of cases) and CGI-SCH (29% of cases), significant functional impairment (total score
ISSN:0165-1781
1872-7123
DOI:10.1016/j.psychres.2013.08.022