Very Low Quality of Life After Acute Stroke: Data From the Efficacy of Nitric Oxide in Stroke Trial

• Published in: Stroke (1970) 2013-12, Vol.44 (12), p.3458-3462
• Main Authors: Sprigg, Nikola, Selby, James, Fox, Lydia, Berge, Eivind, Whynes, David, Bath, Philip M.W
• Format: Article
• Language: English
• Subjects: Activities of Daily Living - psychology; Age Factors; Aged; Aged, 80 and over; Biological and medical sciences; Depression - psychology; Disabled Persons - psychology; Female; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy; Health Status; Humans; Male; Medical sciences; Middle Aged; Nervous system (semeiology, syndromes); Neurology; Outcome Assessment (Health Care); Quality of Life - psychology; Sex Factors; Stroke - psychology; Surveys and Questionnaires; Treatment Outcome; Vascular diseases and vascular malformations of the nervous system
• ISSN: 0039-2499; 1524-4628
• DOI: 10.1161/STROKEAHA.113.002201

BACKGROUND AND PURPOSE—Health-related quality of life, a key outcome after stroke, plays a role in the analysis of treatment cost-effectiveness. Some measures of health-related quality of life allow for a quality of life worse than death; the characteristics of such patients have not been well described. METHODS—Data from the Efficacy of Nitric Oxide in Stroke (ENOS) trial were used to explore health-related quality of life after stroke. The EuroQol questionnaire (EQ-5D) was performed at day 90, and a health utility score (HUS) was calculated. HUS was defined as followspoor-good HUS >0, death HUS=0, and very poor HUS