Development of Biomarkers in Aporrectodea caliginosa and Lumbricus rubellus for Detecting Exposure to Benzo[a]pyrene

The sensitivity of the neutral red retention assay (NRRA0 and cytochrome P450 as biomarkers in the earthworm was tested for potential to detect benzo-a-pyrene (BaP) exposure. As BaP failed to induce ethoxycoumarin-O-dealkylase activity in either of the two earthworm species tested, it is not deemed...

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Bibliographic Details
Published in:Journal of soils and sediments 2002-01, Vol.2 (3), p.148-148
Main Authors: Booth, Lynn H, Heppelthwaite, Vanessa J, O'Halloran, Kathryn
Format: Article
Language:English
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Summary:The sensitivity of the neutral red retention assay (NRRA0 and cytochrome P450 as biomarkers in the earthworm was tested for potential to detect benzo-a-pyrene (BaP) exposure. As BaP failed to induce ethoxycoumarin-O-dealkylase activity in either of the two earthworm species tested, it is not deemed useful as a biomarker for BaP exposure. The NRRA was substantially affected in all cases, indicating that this assay can detect exposure to BaP at a range of concentrations comparable to those found at contaminated sites.
ISSN:1439-0108
DOI:10.1007/BF02988467