Effects of an Extract of Oystercatcher (IT>Haematopus ostralegus Eggs from the Zeehavenkanaal in The Netherlands, and of Its Major Contaminant, Hexachlorobenzene, on the Chicken Embryo

High concentrations of hexachlorobenzene have been found in sediment of the Zeehavenkanaal in the Netherlands. Since oystercatchers feed in the canal, they may be adversely affected by the presence of hexachlorobenzene. In an initial study, chicken embryos were exposed to environmentally relevant co...

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Bibliographic Details
Published in:Environmental toxicology and pharmacology 2002-10, Vol.12 (3), p.147-147
Main Authors: de Roode, Daphne F, Klomp, Anette V, Crum, Steven JH, Eggens, Martin, Bosveld, Albertus TC
Format: Article
Language:English
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Summary:High concentrations of hexachlorobenzene have been found in sediment of the Zeehavenkanaal in the Netherlands. Since oystercatchers feed in the canal, they may be adversely affected by the presence of hexachlorobenzene. In an initial study, chicken embryos were exposed to environmentally relevant concentrations of hexachlorobenzene, resulting in increase density of lymphocytes in the bursa of Fabricius. Eggs of the oystercatchers were extracted, and the extracts, which contained PCBs and hexachlorobenzene were used in a chicken embryo assay at concentrations ranging from 1 to 100% of the amount of contaminants found in one oystercatcher egg. Results showed that the highest dose had the same effect on the density of lymphocytes in the bursa of Fabricius, and also caused ethoxyresorufin O-deethylase induction to increase by 3.5 times.
ISSN:1382-6689