Erectile Dysfunction, Testosterone Deficiency, and Risk of Coronary Heart Disease in a Cohort of Men Living with HIV in Belgium

Erectile dysfunction (ED) is more prevalent in men living with HIV (MLHIV) when compared with age-matched HIV-negative men. This may be related to a premature decline in testosterone levels. In the general population, ED has been associated with an increased risk for coronary heart disease (CHD). Th...

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Bibliographic Details
Published in:Journal of sexual medicine 2013-07, Vol.10 (7), p.1816-1822
Main Authors: De Ryck, Iris, Van Laeken, David, Apers, Ludwig, Colebunders, Robert
Format: Article
Language:English
Subjects:
Adult
Belgium - epidemiology
Coronary Artery Disease - epidemiology
Coronary Heart Disease (CHD)
Cross-Sectional Studies
Erectile Dysfunction (ED)
Erectile Dysfunction - blood
Erectile Dysfunction - epidemiology
HIV Infections - epidemiology
HIV Seropositivity - epidemiology
Humans
Hypogonadism
Male
Middle Aged
MLHIV
Prevalence
Risk Factors
Testosterone - blood
Testosterone - deficiency
Vascular Risk Factor
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Summary:Erectile dysfunction (ED) is more prevalent in men living with HIV (MLHIV) when compared with age-matched HIV-negative men. This may be related to a premature decline in testosterone levels. In the general population, ED has been associated with an increased risk for coronary heart disease (CHD). The aim of this study is to determine the prevalence of ED, testosterone deficiency, and risk of CHD in a cohort of young to middle-aged MLHIV in Belgium. A cross-sectional, observational study among 244 MLHIV attending the outpatient clinic of the Institute of Tropical Medicine in Antwerp. The short version of the international index of erectile function (IIEF-5) questionnaire diagnosed ED (cutoff score ≤21). The 10-year risk score for CHD was calculated. In a subset of men reporting ED, the calculated free testosterone (CFT) was determined using Vermeulen's formula. Testosterone deficiency was defined as CFT
ISSN:1743-6095
1743-6109
DOI:10.1111/jsm.12175