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Role of Cytochrome b5 and α-Tocopherol to Microsomal and Mitochondrial Oxidation

The existence of lipid-radical cycles in membranes as an LPO alternative has been proven. Cytochrome b5 seems to play the key role in the formation of these cycles. The functional role of lipid-radical cycles in cell metabolism, including the positive effect on microsomal and mitochondrial oxidation...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2013-12, Vol.156 (2), p.191-195
Main Authors: Agadzhanyan, Z. S., Doroshchuk, A. D., Shiryaeva, Yu. K., Dmitriev, L. F.
Format: Article
Language:English
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Summary:The existence of lipid-radical cycles in membranes as an LPO alternative has been proven. Cytochrome b5 seems to play the key role in the formation of these cycles. The functional role of lipid-radical cycles in cell metabolism, including the positive effect on microsomal and mitochondrial oxidation, is discussed.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-013-2308-9