An Overview of Methods for Comparative Effectiveness Research

Comparative effectiveness research (CER) is a broad category of outcomes research encompassing many different methods employed by researchers and clinicians from numerous disciplines. The goal of cancer-focused CER is to generate new knowledge to assist cancer stakeholders in making informed decisio...

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Bibliographic Details
Published in:Seminars in radiation oncology 2014, Vol.24 (1), p.5-13
Main Authors: Meyer, Anne-Marie, PhD, Wheeler, Stephanie B., PhD, MPH, Weinberger, Morris, PhD, Chen, Ronald C., MD, MPH, Carpenter, William R., PhD, MHA
Format: Article
Language:English
Subjects:
Case-Control Studies
Cohort Studies
Comparative Effectiveness Research - economics
Comparative Effectiveness Research - methods
Cross-Sectional Studies - methods
Decision Support Techniques
Hematology, Oncology and Palliative Medicine
Humans
Neoplasms - economics
Neoplasms - radiotherapy
Observational Studies as Topic - methods
Radiology
Randomized Controlled Trials as Topic - methods
Research Design
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Summary:Comparative effectiveness research (CER) is a broad category of outcomes research encompassing many different methods employed by researchers and clinicians from numerous disciplines. The goal of cancer-focused CER is to generate new knowledge to assist cancer stakeholders in making informed decisions that will improve health care and outcomes of both individuals and populations. There are numerous CER methods that may be used to examine specific questions, including randomized controlled trials, observational studies, systematic literature reviews, and decision sciences modeling. Each has its strengths and weaknesses. To both inform and serve as a reference for readers of this issue of Seminars in Radiation Oncology as well as the broader oncology community, we describe CER and several of the more commonly used approaches and analytical methods.
ISSN:1053-4296
1532-9461
DOI:10.1016/j.semradonc.2013.09.002