Assessment of chemokine serum levels in epithelial ovarian cancer patients

AIMS AND BACKGROUNDThe study was undertaken to investigate CCL2/MCP-1, CCL3/ MIP-1α, CCL4/MIP-1β, CCL5/RANTES and CXCL8/IL-8 women with epithelial ovarian cancer. METHODS AND STUDY DESIGNSixteen patients diagnosed with epithelial ovarian cancer and 18 healthy women with no evidence of malign neoplas...

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Published in:Tumori 2013-07, Vol.99 (4), p.540-544
Main Authors: Falcão-Júnior, João Oscar Almeida, Teixeira-Carvalho, Andréa, Cândido, Eduardo Batista, Lages, Elisa Lopes, Ferreira Freitas G, Gustavo, Lamaita, Rívia Mara, Freire Bonfim, Lívia Paula, Borges Salera, Rafael, Traiman P, Paulo, da Silva-Filho, Agnaldo Lopes
Format: Article
Language:English
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Summary:AIMS AND BACKGROUNDThe study was undertaken to investigate CCL2/MCP-1, CCL3/ MIP-1α, CCL4/MIP-1β, CCL5/RANTES and CXCL8/IL-8 women with epithelial ovarian cancer. METHODS AND STUDY DESIGNSixteen patients diagnosed with epithelial ovarian cancer and 18 healthy women with no evidence of malign neoplasia (control group) aged from 23 to 89 years (mean ± SEM, 58.7 ± 2.3) were included. The epithelial ovarian cancer patients underwent laparotomy and debulking surgery. Chemokines serum levels were measured by cytometric bead array. Statistical analysis was performed using Mann-Whitney and Kendall's tau. P
ISSN:2038-2529
DOI:10.1700/1361.15108