Synthesis of arylamino-substituted pyrazolo[3,4-d][1,2,4]triazolo[4,3-a]pyrimidinones, pyrazolo[4,3-e][1,2,4]triazolo[4,3-a]pyrimidinones, and their thermal isomerization

The reaction of 1-(4-oxo-1-R-5H-pyrazolo[3,4-d]pyrimidin-6-yl)-4-arylthiosemicarbazides with methyl iodide gave rise to 1,2,4-triazolo-pyrazolopyrimidinones of linear structure, and with dicyclohexylcarbodiimide the products had angular and linear structure. The heating of compounds obtained higher...

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Bibliographic Details
Published in:Russian journal of organic chemistry 2010-02, Vol.46 (2), p.286-290
Main Authors: Vas'kevich, R. I, Bentya, A. V, Staninets, V. I
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Dicyclohexylcarbodiimide
Organic Chemistry
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Summary:The reaction of 1-(4-oxo-1-R-5H-pyrazolo[3,4-d]pyrimidin-6-yl)-4-arylthiosemicarbazides with methyl iodide gave rise to 1,2,4-triazolo-pyrazolopyrimidinones of linear structure, and with dicyclohexylcarbodiimide the products had angular and linear structure. The heating of compounds obtained higher than their melting point resulted in their isomerization into 7-aryl-amino-1-R-1,8-dihydro-4H-pyrazolo[3,4-d]-[1,2,4]triazolo[1,5-a]pyrimidin-4-ones.
ISSN:1070-4280
1608-3393
DOI:10.1134/S1070428010020235