Enhanced metabolism of phosphatidylinositol in Candida tropicalis in association with filamentous growth caused by ethanol

Candida tropicalis Pk 233 grows in filamentous form in ethanol-supplemented medium, and myo-inositol prevents the ethanol ettect [(1979) Bioch!em. Biophys. Res. Commun. 91, 351–355]. Cells, which were grown with ethanol to the log phase, exhibited an increased rate of phosphatidylinositol turnover a...

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Bibliographic Details
Published in:FEBS letters 1987-04, Vol.214 (1), p.127-129
Main Authors: Uejima, Yasuhide, Koga, Teiichiro, Kamihara, Teijiro
Format: Article
Language:English
Subjects:
Biological and medical sciences
Candida tropicalis
cardiolipin
Ethanol
Filamentous growth
Fundamental and applied biological sciences. Psychology
Fungal dimorphism
Growth, nutrition, metabolism, transports, enzymes. Molecular biology
Microbiology
Mycology
phosphatidic acid
phosphatidylcholine
phosphatidylethanolamine
phosphatidylinositol
Phosphatidylinositol turnover
phosphatidylserine
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Summary:Candida tropicalis Pk 233 grows in filamentous form in ethanol-supplemented medium, and myo-inositol prevents the ethanol ettect [(1979) Bioch!em. Biophys. Res. Commun. 91, 351–355]. Cells, which were grown with ethanol to the log phase, exhibited an increased rate of phosphatidylinositol turnover as judged by pulse-chase experiments with 32Pi. Such enhanced metabolism of phosphatidylinositol was not observed in fully developed filamentous cells at the stationary phase or in yeast-like cells which were grown without added ethanol or with ethanol plus myo-inositol. The metabolism of other phospholipids was not affected by ethanol.
ISSN:0014-5793
1873-3468
DOI:10.1016/0014-5793(87)80026-1