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Organization of the 5.8S, 16-18S, and 23-28S ribosomal RNA genes of Cephalosporium acremonium

A 9.2 kb Pst1 restriction fragment, repeated tandemly head-to-tail in the genome, contains the 5.8S, 16-18S, and 23-28S ribosomal RNA (rRNA) genes of Cephalosporium acremonium , a filamentous fungus used at the industrial scale for production of cephalosporin antibiotics. These genes were ordered wi...

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Bibliographic Details
Published in:Current genetics 1987-01, Vol.12 (3), p.209-214
Main Authors: Carr, L.G, Skatrud, P.L, Ingolia, T.D, Queener, S.W
Format: Article
Language:English
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Summary:A 9.2 kb Pst1 restriction fragment, repeated tandemly head-to-tail in the genome, contains the 5.8S, 16-18S, and 23-28S ribosomal RNA (rRNA) genes of Cephalosporium acremonium , a filamentous fungus used at the industrial scale for production of cephalosporin antibiotics. These genes were ordered with the 5.8S gene located between the 16-18S and 23-28S rRNA genes. The order of the 16-18S, 5.8S, and 23-28S rRNA genes observed in C. acremonium is the same as that observed in rRNA repeats of many other lower eucaryotes, e.g. S. cerevisiae, Aspergillus nidulans , and Neurospora crassa .
ISSN:0172-8083
1432-0983
DOI:10.1007/BF00436881