Xylose catabolism by a mutant of Streptomyces chrysomallus altered in the regulation of D-glucose isomerase

A mutant of S. chrysomallus with a D-glucose isomerase inducible by D-glucose or its catabolites was characterized. In contrast to the wild-type strain it showed a decreased catabolite repression by D-glucose of D-xylose consumption and a constitutive pentose phosphate pathway as well. A hypothesis...

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Bibliographic Details
Published in:Biotechnology letters 1987-12, Vol.9 (12), p.861-866
Main Authors: HÄNEL, F, ROTH, M, NEIGENFIND, M, GRÄFE, U, BORMANN, E. J
Format: Article
Language:English
Subjects:
Biological and medical sciences
Biology of microorganisms of confirmed or potential industrial interest
Biotechnology
Fundamental and applied biological sciences. Psychology
Mission oriented research
mutants
Physiology and metabolism
Streptomyces chrysomallus
xylose
xylose isomerase
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Summary:A mutant of S. chrysomallus with a D-glucose isomerase inducible by D-glucose or its catabolites was characterized. In contrast to the wild-type strain it showed a decreased catabolite repression by D-glucose of D-xylose consumption and a constitutive pentose phosphate pathway as well. A hypothesis concerning altered induction pattern of its D-glucose isomerase is discussed.
ISSN:0141-5492
1573-6776
DOI:10.1007/BF01026199