rapid screening of Streptomyces avermitilis production strains

A simple biological test based on paralysis of movement of a free-living nematode Caenorhabditis elegans , suitable for screening of mutant strains of S. avermitilis producing a complex of avermectins is described.

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Bibliographic Details
Published in:Biotechnology techniques 1988, Vol.2 (1), p.47-52
Main Authors: Novak, J, Cimburkova, E, Vanek, Z
Format: Article
Language:English
Subjects:
avermectins
bioassays
biosynthesis
Caenorhabditis
Caenorhabditis elegans
mutants
paralysis
screening
Streptomyces
Streptomyces avermitilis
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Description
Summary:A simple biological test based on paralysis of movement of a free-living nematode Caenorhabditis elegans , suitable for screening of mutant strains of S. avermitilis producing a complex of avermectins is described.
ISSN:0951-208X
1573-6784