Invertebrate vasopressin/oxytocin homologs characterization of peptides from conus Geographus and conus striatus venoms

The vasopressin-oxytocin family of peptides is of very ancient lineage, found in organisms as diverse as hydra and man. Although these peptides have been intensively studied in vertebrates, the presumably more extensive invertebrate series was defined primarily by immunological methods. In this repo...

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Bibliographic Details
Published in:The Journal of biological chemistry 1987-11, Vol.262 (33), p.15821-15824
Main Authors: CRUZ, L. J, DE SANTOS, V, ZAFARALLA, G. C, RAMILO, C. A, ZEIKUS, R, GRAY, W. R, OLIVERA, B. M
Format: Article
Language:English
Subjects:
Aminoacids, peptides. Hormones. Neuropeptides
Analytical, structural and metabolic biochemistry
Biological and medical sciences
Conus geographus
Fundamental and applied biological sciences. Psychology
oxytocin
Proteins
vasopressin
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Summary:The vasopressin-oxytocin family of peptides is of very ancient lineage, found in organisms as diverse as hydra and man. Although these peptides have been intensively studied in vertebrates, the presumably more extensive invertebrate series was defined primarily by immunological methods. In this report, the authors describe the purification and structures of two peptides of the vasopressin-oxytocin family from molluscs ("Conopressins"), which were found in the venom of fish-hunting marine snails of the genus Conus .
ISSN:0021-9258
1083-351X