Mesenteric fat thickness is associated with increased risk of obstructive sleep apnoea

• Published in: Respirology (Carlton, Vic.) Vic.), 2014-01, Vol.19 (1), p.92-97
• Main Authors: Liu, Kin Hung, Chu, Winnie C.W., To, Kin Wang, Ko, Fanny W.S., Ng, Susanna S.S., Ngai, Jenny C.L., Chan, Jeff Wai Sang, Ahuja, Anil T., Hui, David S.C.
• Format: Article
• Language: English
• Subjects: Adipose Tissue - diagnostic imaging; Adipose Tissue - pathology; Body Mass Index; China - epidemiology; Female; Humans; Incidence; Magnetic Resonance Imaging; Male; mesenteric fat; Mesentery - diagnostic imaging; Mesentery - pathology; Metabolic Syndrome - complications; Metabolic Syndrome - diagnosis; Middle Aged; Obesity - complications; Obesity - diagnosis; obstructive sleep apnoea; Polysomnography; preperitoneal fat; Risk Factors; Sleep Apnea, Obstructive - diagnosis; Sleep Apnea, Obstructive - epidemiology; Sleep Apnea, Obstructive - etiology; subcutaneous fat; Tomography, X-Ray Computed; Ultrasonography; ultrasound
• ISSN: 1323-7799; 1440-1843
• DOI: 10.1111/resp.12164

Background and objective Mesenteric fat is a type of intraperitoneal adipose tissue draining into portal circulation. The objective of this study was to investigate the relationships between mesenteric fat thickness and obstructive sleep apnoea (OSA) in patients with suspected OSA. Methods One hundred forty‐nine subjects (men: 114; women: 35) with suspected OSA underwent ultrasound examinations of mesenteric, preperitoneal and subcutaneous fat thickness after overnight polysomnography. Body mass index (BMI) and neck circumference were recorded. Results The subjects with OSA (n = 130, apnoea/hypopnoea index (AHI) >5/h) had greater neck circumference, higher BMI, and greater mesenteric and preperitoneal fat thickness than those without OSA (n = 19, AHI ≤ 5/h). There was positive correlation of AHI with mesenteric (r = 0.43, P