Guillain-Barré syndrome following herpes zoster in a patient with systemic sclerosis

Abstract We report the case of a patient with systemic sclerosis (SSc) who developed Guillain-Barré syndrome (GBS) 6 weeks after herpes zoster. Muscle weakness developed first, and thereafter severely in the muscles in the same segment as the zoster. Serum anti-GM1 and -GD1b IgM autoantibodies were...

Full description

Saved in:
Bibliographic Details
Published in:Modern rheumatology 2001-09, Vol.11 (3), p.251-254
Main Authors: Yamaguchi, M., Chiba, A., Yanagawa, T., Mato, T., Hirai, K., Inoue, T., Oya, Y., Kusunoki, S., Ito, K., Yamamoto, K.
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract We report the case of a patient with systemic sclerosis (SSc) who developed Guillain-Barré syndrome (GBS) 6 weeks after herpes zoster. Muscle weakness developed first, and thereafter severely in the muscles in the same segment as the zoster. Serum anti-GM1 and -GD1b IgM autoantibodies were detected in the acute phase. The clinical course and the findings of nerve conduction studies and a sural nerve biopsy were compatible with GBS accompanied by underlying chronic polyneuropathy. SSc might have affected the neurological manifestation via the development of underlying neuropathy and a possible contribution to the autoimmune basis in GBS.
ISSN:1439-7595
1439-7609
DOI:10.3109/s101650170014