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Vasculitis following implantation of a ventriculoperitoneal shunt tube made of silicone

Abstract A 56-year-old man presented with hyperproteinemia and renal dysfunction associated with antineutrophil cytoplasmic antibodies (ANCA). He had had a ventriculoperitoneal shunt tube made of silicone implanted 4 years earlier. In his renal biopsy, necrotizing crescentic glomerulonephritis was i...

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Bibliographic Details
Published in:Modern rheumatology 2003-03, Vol.13 (1), p.73-75
Main Authors: Bohgaki, M., Mukai, M., Notoya, A., Kohno, M., Takada, A.
Format: Article
Language:English
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Summary:Abstract A 56-year-old man presented with hyperproteinemia and renal dysfunction associated with antineutrophil cytoplasmic antibodies (ANCA). He had had a ventriculoperitoneal shunt tube made of silicone implanted 4 years earlier. In his renal biopsy, necrotizing crescentic glomerulonephritis was identified: tests for both myeloperoxidase ANCA and proteinase 3 ANCA were initially weakly positive. Antinuclear and other autoantibodies were also present. We diagnosed ANCA-associated vasculitis, probably induced by the silicone tube.
ISSN:1439-7595
1439-7609
DOI:10.3109/s101650300011