Can platelet indices predict obstruction level of pulmonary vascular bed in patients with acute pulmonary embolism?

• Published in: The clinical respiratory journal 2014-01, Vol.8 (1), p.33-40
• Main Authors: Günay, Ersin, Sarinc Ulasli, Sevinc, Kacar, Emre, Halici, Bilal, Unlu, Ebru, Tünay, Kamil, Ozkececi, Gulay, Koken, Tulay, Unlu, Mehmet
• Format: Article
• Language: English
• Subjects: Acute Disease; acute pulmonary embolism; Aged; computed tomography pulmonary arterial obstruction index ratio; computerised tomography; Embolisms; Female; Humans; Length of Stay; Male; Mean Platelet Volume; Middle Aged; Platelet Function Tests; platelet indices; Pulmonary Artery - pathology; Pulmonary Embolism - diagnosis; Pulmonary Embolism - diagnostic imaging; Pulmonary Embolism - physiopathology; Retrospective Studies; Severity of Illness Index; severity of pulmonary embolism; Tomography; Tomography, X-Ray Computed; Ultrasonography
• ISSN: 1752-6981; 1752-699X
• DOI: 10.1111/crj.12031

Introduction Computed tomography pulmonary arterial obstruction index ratio (CTPAOIR) is related with the severity of pulmonary embolism (PE). Platelet indices including mean platelet volume (MPV), platelet distribution width (PDW) are reported to be increased in acute PE. Objective In this study, we aimed to evaluate the relationship between CTPAOIR and platelet indices and the utility of these parameters in the determination of PE severity. Materials and Methods   We retrospectively analysed the demographic data, clinical probability scores, laboratory data and echocardiographic findings of 63 acute PE patients who were diagnosed by pulmonary arterial computed tomography angiography. Results The hospital records of 38 (60.3%) male and 25 (39.7%) female patients with acute PE and 29 (58%) male and 21 (42%) female healthy control were evaluated (P = 0.803). The mean value of MPV, PDW levels, platelet counts and red cell distribution width levels were higher in PE groups than in control subjects (P