Amino acid/KI as multi-functional synergistic catalysts for cyclic carbonate synthesis from CO2 under mild reaction conditions: a DFT corroborated study

• Published in: Dalton transactions : an international journal of inorganic chemistry 2014-02, Vol.43 (5), p.2023-2031
• Main Authors: Roshan, Kuruppathparambil Roshith, Kathalikkattil, Amal Cherian, Tharun, Jose, Kim, Dong Woo, Won, Yong Sun, Park, Dae Won
• Format: Article
• Language: English
• Subjects: Amino Acids - chemistry; Carbon Dioxide - chemistry; Carbonates - chemical synthesis; Carbonates - chemistry; Catalysis; Cyclization; Epoxy Compounds - chemistry; Molecular Structure; Potassium Iodide - chemistry; Quantum Theory
• ISSN: 1477-9234
• DOI: 10.1039/c3dt52830h

Naturally occurring amino acids were identified as efficient co-catalysts for the alkali metal halide-mediated synthesis of cyclic carbonates from carbon dioxide and epoxides under mild, solvent free reaction conditions. The binary system of histidine/potassium iodide gave an appreciable turnover number of 535 for propylene oxide in 3 h. Detailed studies evaluating a variety of amino acids revealed that the basic amino acids afforded better conversion rates. The formation of a seven membered ring involving the zwitterionic ends of the amino acid, the metal halide, and the epoxide was considered to accelerate the catalysis rate. Density functional theory calculations were performed for the first time on amino acid co-catalyzed cycloaddition to provide further evidence for this hypothesis. The iodide ions of the alkali metal halide displayed excellent synergism with the hydrogen bonding groups of the amino acids in the production of cyclic carbonates, whereas bromide and chloride anions functioned less efficiently. The utilization of amino acids to enhance the catalytic activity of the cheap and eco-friendly alkali metal halides for cyclic carbonate synthesis represents a cost-effective, greener route towards the chemical fixation of carbon dioxide.