SERS-based competitive immunoassay of troponin I and CK-MB markers for early diagnosis of acute myocardial infarction

We report a SERS-based competitive immunoassay technique for the early diagnosis of acute myocardial infarction (AMI). Simultaneous quantification of the dual cardiac markers, CK-MB and troponin I, was achieved by single wavelength excitation.

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2014-01, Vol.50 (9), p.1058-1060
Main Authors: Chon, Hyangah, Lee, Sangyeop, Yoon, Soo-Young, Lee, Eun Kyu, Chang, Soo-Ik, Choo, Jaebum
Format: Article
Language:English
Subjects:
Acute Disease
Biomarkers - analysis
Creatine Kinase, MB Form - analysis
Humans
Immunoassay
Magnetics
Myocardial Infarction - diagnosis
Spectrum Analysis, Raman
Troponin I - analysis
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Description
Summary:We report a SERS-based competitive immunoassay technique for the early diagnosis of acute myocardial infarction (AMI). Simultaneous quantification of the dual cardiac markers, CK-MB and troponin I, was achieved by single wavelength excitation.
ISSN:1359-7345
1364-548X
DOI:10.1039/c3cc47850e