In vivo diagnostics of human knee cartilage lesions using delayed CBCT arthrography

ABSTRACT The aim of this study was to investigate the feasibility of delayed cone beam (CBCT) arthrography for clinical diagnostics of knee cartilage lesions. Knee joints with cartilage lesions were imaged using native radiography, MRI, and delayed CBCT arthrography techniques in vivo. The joints we...

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Bibliographic Details
Published in:Journal of orthopaedic research 2014-03, Vol.32 (3), p.403-412
Main Authors: Kokkonen, Harri T., Suomalainen, Juha-Sampo, Joukainen, Antti, Kröger, Heikki, Sirola, Joonas, Jurvelin, Jukka S., Salo, Jari, Töyräs, Juha
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Arthrography - methods
cartilage lesions
Cartilage, Articular - injuries
computed tomography
Cone-Beam Computed Tomography - methods
contrast agent diffusion
delayed CBCT arthrography
Female
Humans
Knee Injuries - diagnostic imaging
Male
Middle Aged
Osteoarthritis, Knee - diagnostic imaging
osteoarthrosis
Young Adult
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Summary:ABSTRACT The aim of this study was to investigate the feasibility of delayed cone beam (CBCT) arthrography for clinical diagnostics of knee cartilage lesions. Knee joints with cartilage lesions were imaged using native radiography, MRI, and delayed CBCT arthrography techniques in vivo. The joints were imaged three times with CBCT, just before, immediately after (arthrography) and 45 min after the intra‐articular injection of contrast agent. The arthrographic images enabled sensitive detection of the cartilage lesions. Use of arthrographic and delayed images together with their subtraction image enabled also detection of cartilage with inferior integrity. The contrast agent partition in intact cartilage (ICRS grade 0) was lower (p 
ISSN:0736-0266
1554-527X
DOI:10.1002/jor.22521