A Softgel Dietary Supplement Containing Esterified Plant Sterols and Stanols Improves the Blood Lipid Profile of Adults with Primary Hypercholesterolemia: A Randomized, Double-Blind, Placebo-Controlled Replication Study

Abstract A well-controlled clinical trial previously demonstrated the efficacy of a novel softgel dietary supplement providing 1.8 g/day esterified plant sterols and stanols, as part of the National Cholesterol Education Program Therapeutic Lifestyle Changes diet, to improve the fasting lipid profil...

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Bibliographic Details
Published in:Journal of the Academy of Nutrition and Dietetics 2014-02, Vol.114 (2), p.244-249
Main Authors: McKenney, James M., PharmD, Jenks, Belinda H., PhD, RD, Shneyvas, Ed, PhD, MBA, Brooks, James R., PhD, Shenoy, Sonia F., PhD, RD, Cook, Chad M., PhD, Maki, Kevin C., PhD
Format: Article
Language:English
Subjects:
Adult
Aged
Cholesterol - blood
Cholesterol, HDL - blood
Cholesterol, LDL - blood
Diet
Dietary Supplements
Double-Blind Method
Esterification
Female
Gastroenterology and Hepatology
Humans
Hypercholesterolemia - drug therapy
Internal Medicine
Lipids - blood
Male
Middle Aged
Phytosterols - administration & dosage
Placebos
Sitosterols - administration & dosage
Triglycerides - blood
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Summary:Abstract A well-controlled clinical trial previously demonstrated the efficacy of a novel softgel dietary supplement providing 1.8 g/day esterified plant sterols and stanols, as part of the National Cholesterol Education Program Therapeutic Lifestyle Changes diet, to improve the fasting lipid profile of men and women with primary hypercholesterolemia (fasting low-density lipoprotein [LDL] cholesterol ≥130 and
ISSN:2212-2672
DOI:10.1016/j.jand.2013.09.023