Glutamine effects on brain growth in very preterm children in the first year of life

Summary Background & aims Glutamine supplementation in the neonatal period has been associated with increased brain structure volumes at school-age in very preterm children. The aim of this study was to clarify the emergence and specificity of differences in brain structure volumes, using growth...

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Bibliographic Details
Published in:Clinical nutrition (Edinburgh, Scotland) Scotland), 2014-02, Vol.33 (1), p.69-74
Main Authors: de Kieviet, Jorrit F, Vuijk, Pieter J, van den Berg, Anemone, Lafeber, Harrie N, Oosterlaan, Jaap, van Elburg, Ruurd M
Format: Article
Language:English
Subjects:
Biological and medical sciences
Body Weight
Brain - drug effects
Brain - growth & development
Brain structure volumes
Cephalometry
Child
Child Development - drug effects
Feeding. Feeding behavior
Female
Follow-Up Studies
Fundamental and applied biological sciences. Psychology
Gastroenterology and Hepatology
Glutamine
Glutamine - administration & dosage
Growth
Head circumference
Humans
Infant
Infant, Premature - growth & development
Intensive Care Units, Neonatal
Magnetic Resonance Imaging
Male
Multilevel modeling analyses
Prematurity
Vertebrates: anatomy and physiology, studies on body, several organs or systems
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Summary:Summary Background & aims Glutamine supplementation in the neonatal period has been associated with increased brain structure volumes at school-age in very preterm children. The aim of this study was to clarify the emergence and specificity of differences in brain structure volumes, using growth trajectories of head circumference, weight, and length. Methods Sixty-five very preterm (
ISSN:0261-5614
1532-1983
DOI:10.1016/j.clnu.2013.03.019