Detection of hepatitis B virus in the cerumen of patients with chronic hepatitis B infection

To investigate hepatitis B virus DNA in the cerumen of hepatitis B virus infected patients. This study comprised 30 confirmed cases of chronic hepatitis B. Patients' serum samples were examined for hepatitis B surface antigen and antibodies using enzyme immunoassay systems. The presence of hepa...

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Bibliographic Details
Published in:Journal of laryngology and otology 2013-11, Vol.127 (11), p.1065-1066
Main Authors: Eftekharian, A, Moghaddasi, H, Gachkar, L, Amlashi, S S A
Format: Article
Language:English
Subjects:
Antibodies
Antigens
Body fluids
Cerumen - virology
Disease prevention
DNA, Viral - isolation & purification
Epidemiology
Female
Hepatitis B
Hepatitis B virus
Hepatitis B virus - genetics
Hepatitis B virus - isolation & purification
Hepatitis B, Chronic - virology
Hepatitis C
HIV
Human immunodeficiency virus
Humans
Infections
Liver
Main Articles
Male
Middle Aged
Patients
Serology
Vagina
Viruses
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Summary:To investigate hepatitis B virus DNA in the cerumen of hepatitis B virus infected patients. This study comprised 30 confirmed cases of chronic hepatitis B. Patients' serum samples were examined for hepatitis B surface antigen and antibodies using enzyme immunoassay systems. The presence of hepatitis B virus DNA in cerumen was investigated using a polymerase chain reaction test. All of the samples were positive for hepatitis B surface antigen and negative for hepatitis B surface antibodies. Hepatitis virus DNA was detected in two cerumen samples (6.6 per cent of patients). Cerumen can be a potential source of transmission of hepatitis B virus.
ISSN:0022-2151
1748-5460
DOI:10.1017/S0022215113002314