Prophylaxis and therapy of virulent encephalomyocarditis virus infection in mice by monoclonal antibodies

Two encephalomyocarditis virus (EMCV) neutralizing monoclonal antibodies (MAs), recognizing different determinants on EMCV, were both able to protect mice prophylactically and therapeutically against a lethal dose of EMCV.

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Bibliographic Details
Published in:Archives of virology 1988-03, Vol.98 (1-2), p.123-130
Main Authors: VLASPOLDER, F, KRAAIJEVELD, C. A, VAN BUUREN, R, HARMSEN, M, BENAISSA-TROUW, B. J, SNIPPE, H
Format: Article
Language:English
Subjects:
Animal viral diseases
Biological and medical sciences
encephalomyocarditis virus
Infectious diseases
Medical sciences
Viral diseases
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Description
Summary:Two encephalomyocarditis virus (EMCV) neutralizing monoclonal antibodies (MAs), recognizing different determinants on EMCV, were both able to protect mice prophylactically and therapeutically against a lethal dose of EMCV.
ISSN:0304-8608
1432-8798
DOI:10.1007/BF01321013