Uptake of Engineered Gold Nanoparticles into Mammalian Cells

Gold nanoparticles (GNPs) are used to transfer genetic and medicinal properties into the cell. Adsortion and chemosorption can be used to functionalize GNPs, while penetrating peptides can deliver GNPs into mammalian cells.

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Bibliographic Details
Published in:Chemical reviews 2014-01, Vol.114 (2), p.1258-1288
Main Authors: Dykman, Lev A, Khlebtsov, Nikolai G
Format: Article
Language:English
Subjects:
Animals
Biochemistry
Cell Line
Cells - metabolism
Chemical engineering
Gold
Gold - chemistry
Gold - metabolism
Gold - pharmacokinetics
Humans
Ligands
Metal Nanoparticles - chemistry
Nanoparticles
Oligonucleotides - chemistry
Oligonucleotides - pharmacokinetics
Particle Size
Peptides
Surface Properties
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Description
Summary:Gold nanoparticles (GNPs) are used to transfer genetic and medicinal properties into the cell. Adsortion and chemosorption can be used to functionalize GNPs, while penetrating peptides can deliver GNPs into mammalian cells.
ISSN:0009-2665
1520-6890
DOI:10.1021/cr300441a