Early postoperative complications after stapled vs handsewn restorative proctocolectomy with ileal pouch-anal anastomosis in 148 patients with familial adenomatous polyposis coli: a matched-pair analysis

• Published in: Colorectal disease 2014-02, Vol.16 (2), p.116-122
• Main Authors: Ganschow, P., Warth, R., Hinz, U., Büchler, M. W., Kadmon, M.
• Format: Article
• Language: English
• Subjects: Abscess; Adenomatous Polyposis Coli - surgery; Adolescent; Adult; Anastomosis, Surgical - methods; Anastomotic Leak; Case-Control Studies; Child; Cohort Studies; Colonic Pouches; FAP; Female; Humans; ileal pouch-anal anastomosis; IPAA; Male; Middle Aged; Postoperative Complications; pouch; Proctocolectomy, Restorative - methods; restorative proctocolectomy; Retrospective Studies; Surgical Stapling; Suture Techniques; Treatment Outcome; Young Adult
• ISSN: 1462-8910; 1463-1318
• DOI: 10.1111/codi.12385

Aim Restorative proctocolectomy with ileal pouch‐anal anastomosis for patients with familial adenomatous polyposis (FAP) and ulcerative colitis (UC) has been modified from a transanal hand‐suture after mucosectomy to a stapled ileal pouch‐anal anastomosis (IPAA) without mucosectomy. Better functional results favour stapled anastomosis; however, stapled anastomosis results in higher rates of adenomas in persisting anorectal mucosa. The purpose of this study was to compare the two techniques of pouch‐anal anastomosis with respect to early postoperative complications in a collective of FAP patients. Method The study was performed as a matched‐pair analysis. Data were obtained from a prospectively collected database. Results The overall rate of postoperative complications was higher after stapled IPAA (31% stapled vs 23% handsewn), with anastomotic stricture occurring in 24.3% (stapled) and 16.2% (handsewn) (P = 0.22). Any leakage or pelvic abscess formation after stapled anastomosis occurred within 30 days in almost all patients, whereas these were mainly diagnosed between 30 days and 6 months after handsewn IPAA. A laparoscopic approach was used in 56.7% of patients in the stapled group but in only two patients in the handsewn group. Intra‐operative blood loss was significantly higher in the handsewn group (mean ± SD: 699 ± 511 ml vs 369 ± 343 ml; P