Synthesis of Dialkyl {(aryl)[2,2-Dimethyl-4-oxo-6-(Piperidin-1-yl)-4 H -[1,3]Dioxin-5-yl]Methyl}Phosphonate by Reaction of Meldrum's Acid, Aryl Aldehydes and Trialkyl Phosphites in the Presence of Piperidine

A four-component reaction between Meldrum's acid, aryl aldehydes with trialkyl phosphites in the presence of piper-idine has been developed. The reaction affords dialkyl {(aryl)[2,2-dimethyl-4-oxo-6-(piperidin-1-yl)-4 H-[1,3]dioxin-5-yl]methyl}phosphonate in moderate to good yields in a one-pot...

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Bibliographic Details
Published in:Journal of chemical research 2013-07, Vol.37 (7), p.402-403
Main Authors: Khosravi, Reza, Hosseini-Tabatabaei, Mohammad R, ghaniha, Ali
Format: Article
Language:English
Subjects:
Aldehydes
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Summary:A four-component reaction between Meldrum's acid, aryl aldehydes with trialkyl phosphites in the presence of piper-idine has been developed. The reaction affords dialkyl {(aryl)[2,2-dimethyl-4-oxo-6-(piperidin-1-yl)-4 H-[1,3]dioxin-5-yl]methyl}phosphonate in moderate to good yields in a one-pot process.
ISSN:1747-5198
2047-6507
DOI:10.3184/174751913X13701025495780