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Fischer carbene complex with hydrophilic OEG-tentacles decorates antibody surface with in situgenerated gold nanoparticles for rapid, sensitive, visual detection of proteins
Gold nanoparticles were generated and immobilized on the surface of an antibody conjugated with a hydrophilic Fischer carbene complex with oligo-ethyleneglycol tethers, enabling rapid visual detection of the corresponding antigen specifically, even in serum, at a very low concentration without any i...
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Published in: | Analytical methods 2013-12, Vol.6 (2), p.351-354 |
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Main Authors: | , , |
Format: | Article |
Language: | English |
Subjects: | |
Online Access: | Get full text |
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Summary: | Gold nanoparticles were generated and immobilized on the surface of an antibody conjugated with a hydrophilic Fischer carbene complex with oligo-ethyleneglycol tethers, enabling rapid visual detection of the corresponding antigen specifically, even in serum, at a very low concentration without any instrumentation. |
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ISSN: | 1759-9660 1759-9679 |
DOI: | 10.1039/c3ay41903g |