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Fischer carbene complex with hydrophilic OEG-tentacles decorates antibody surface with in situgenerated gold nanoparticles for rapid, sensitive, visual detection of proteins

Gold nanoparticles were generated and immobilized on the surface of an antibody conjugated with a hydrophilic Fischer carbene complex with oligo-ethyleneglycol tethers, enabling rapid visual detection of the corresponding antigen specifically, even in serum, at a very low concentration without any i...

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Bibliographic Details
Published in:Analytical methods 2013-12, Vol.6 (2), p.351-354
Main Authors: Ray, Namrata, Sawoo, Sudeshna, Sarkar, Amitabha
Format: Article
Language:English
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Summary:Gold nanoparticles were generated and immobilized on the surface of an antibody conjugated with a hydrophilic Fischer carbene complex with oligo-ethyleneglycol tethers, enabling rapid visual detection of the corresponding antigen specifically, even in serum, at a very low concentration without any instrumentation.
ISSN:1759-9660
1759-9679
DOI:10.1039/c3ay41903g