A New ent -Kaurane Deterpenoid from Isodon Excisoides (Sun ex C. H. Hu) C. Y. Wu et H. W. Li

A new ent-kaurane diterpenoid, excisoidesin (1), was isolated from the acetone extract of the leaves of Isodon excisoides (Sun ex C. H. Hu) C. Y. Wu et H. W. Li, along with kamebacetal B (2), glaucocalyxin A (3), leukamenin E (4), kamebanin (5) and wangzaozin A (6). The structure of the new compound...

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Bibliographic Details
Published in:Journal of chemical research 2004-10, Vol.2004 (10), p.697-698
Main Authors: Ding, Lan, Wang, Han, Liu, Guoan, Yang, Dongjuan
Format: Article
Language:English
Subjects:
Acetone
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Summary:A new ent-kaurane diterpenoid, excisoidesin (1), was isolated from the acetone extract of the leaves of Isodon excisoides (Sun ex C. H. Hu) C. Y. Wu et H. W. Li, along with kamebacetal B (2), glaucocalyxin A (3), leukamenin E (4), kamebanin (5) and wangzaozin A (6). The structure of the new compound was determined as 7?,14?,18-trihydroxy-ent-kaur-16-en-3,15-dione by spectroscopic methods. Compound 1-6 showed significant cytotoxic activity against human tumor Bel-7402 cells.
ISSN:1747-5198
2047-6507
DOI:10.3184/0308234043431898