A Three-Component Novel Synthesis of 1-[Aryl(Thioacetamido)Methyl]-2-Naphthol Derivatives

A three-component reaction between 2-naphthol, an aryl aldehydes and thioacetamide catalysed by p-toluenesulfonic acid under reflux conditions provided a simple and efficient one-pot route for the synthesis of 1-[aryl(thioaceta mido)methyl]-2-naphthol derivatives in excellent yields.

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Published in:Journal of chemical research 2012-09, Vol.36 (9), p.510-511
Main Authors: Hassanabadi, Alireza, Hosseini-Tabatabaei, Mohammad R
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Language:English
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Aldehydes
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description A three-component reaction between 2-naphthol, an aryl aldehydes and thioacetamide catalysed by p-toluenesulfonic acid under reflux conditions provided a simple and efficient one-pot route for the synthesis of 1-[aryl(thioaceta mido)methyl]-2-naphthol derivatives in excellent yields.
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title A Three-Component Novel Synthesis of 1-[Aryl(Thioacetamido)Methyl]-2-Naphthol Derivatives
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