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N-Methyl/phenyl furan derivatives as dipolarophiles for synthesis of spiro isoxazolidine derivatives with ?-chloro and simple nitrones

1,3-Dipolar cycloaddition reactions of ?-chloro and simple nitrones have been studied with novel ?-N-methyl/phenyl furan derivatives as new dipolarophiles. The reactions are found to be highly regioselective to afford single 5-spiro isoxazolidines with high yield in a short reaction time.

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Bibliographic Details
Published in:Journal of chemical research 2010-03, Vol.34 (3), p.147-150
Main Authors: Chakraborty, Bhaskar, Sharma, Prawin Kumar, Rai, Neelam, Kafley, Saurav, Chhetri, Manjit
Format: Article
Language:English
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Summary:1,3-Dipolar cycloaddition reactions of ?-chloro and simple nitrones have been studied with novel ?-N-methyl/phenyl furan derivatives as new dipolarophiles. The reactions are found to be highly regioselective to afford single 5-spiro isoxazolidines with high yield in a short reaction time.
ISSN:1747-5198
2047-6507
DOI:10.3184/030823410X12675422347141