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Up in Smoke? A Preliminary Open-Label Trial of Nicotine Replacement Therapy and Cognitive Behavioral Motivational Enhancement for Smoking Cessation Among Youth in Los Angeles

In 2008-2009, we conducted a 6-week, open-label trial of transdermal nicotine replacement therapy and practical counseling for 34 adolescents seeking smoking cessation in Los Angeles. Dependent outcomes were study retention, use of the patch, and 7-day quit status at the end-of-study and at follow-u...

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Bibliographic Details
Published in:Substance use & misuse 2013-12, Vol.48 (14), p.1553-1562
Main Authors: Swanson, Aimee-Noelle, Shoptaw, Steven, Heinzerling, Keith Gregory, Wade, Adam C., Worley, Matthew, McCracken, James, Wilson, Sarah A., Asarnow, Joan, London, Edythe D.
Format: Article
Language:English
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Summary:In 2008-2009, we conducted a 6-week, open-label trial of transdermal nicotine replacement therapy and practical counseling for 34 adolescents seeking smoking cessation in Los Angeles. Dependent outcomes were study retention, use of the patch, and 7-day quit status at the end-of-study and at follow-up visits. Predictors of outcomes included cigarette dependence, withdrawal symptoms, demographic and psychiatric measures, and other substance use. Variables significant in bivariate analysis (p < .10) were retained in a multivariate model. Subjects had significant pre-to-post reductions in quit rates, dependence, and withdrawal symptoms. Subjects also reported a high number of comorbidities. Implications for clinicians are discussed.
ISSN:1082-6084
1532-2491
DOI:10.3109/10826084.2013.808218