Rarity of Severe Bleeding and Perforation in Endoscopic Ultrasound-Guided Fine Needle Aspiration for Submucosal Tumors

Background Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is an established procedure for the pathological diagnosis of gastrointestinal submucosal tumors (SMTs). Although bleeding and perforation are potentially severe complications of EUS-FNA, the incidences and severities of these...

Full description

Saved in:
Bibliographic Details
Published in:Digestive diseases and sciences 2013-09, Vol.58 (9), p.2634-2638
Main Authors: Hamada, Tsuyoshi, Yasunaga, Hideo, Nakai, Yousuke, Isayama, Hiroyuki, Horiguchi, Hiromasa, Matsuda, Shinya, Fushimi, Kiyohide, Koike, Kazuhiko
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biochemistry
Endoscopic Ultrasound-Guided Fine Needle Aspiration - adverse effects
Endoscopy
Female
Gastroenterology
Gastrointestinal Hemorrhage - etiology
Gastrointestinal Neoplasms - diagnosis
Hepatology
Humans
Intestinal Mucosa - blood supply
Intestinal Mucosa - pathology
Male
Medicine
Medicine & Public Health
Middle Aged
Oncology
Original Article
Retrospective Studies
Transplant Surgery
Tumors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is an established procedure for the pathological diagnosis of gastrointestinal submucosal tumors (SMTs). Although bleeding and perforation are potentially severe complications of EUS-FNA, the incidences and severities of these complications have not yet been fully evaluated because of their relative rarity. Aim The purpose of this study was to evaluate the incidences and mortality of severe bleeding and perforation in patients who underwent EUS-FNA for SMTs. Methods The records of 1,135 consecutive patients who underwent EUS-FNA for SMTs at 219 hospitals, with low- to high-volume, were reviewed using a Japanese nationwide administrative database. Results Of the targeted lesions 73.5 % were located in the stomach, 13.4 % in the esophagus, 8.2 % in the duodenum, and 4.9 % at other sites. Five patients (0.44 %) experienced severe bleeding requiring red blood cell transfusion or endoscopic treatment, with none experiencing perforation. Only one patient (0.09 %) died in-hospital within 30 days of EUS-FNA (0.09 %), with death not associated with bleeding or perforation. Conclusions EUS-FNA is safe in evaluating SMTs, with low risks of bleeding and perforation.
ISSN:0163-2116
1573-2568
DOI:10.1007/s10620-013-2717-7