Relationship between dietary intake of organic chemicals and their concentrations in human adipose tissue and breast milk

It is demonstrated that the bioaccumulation of organics in human tissues was positively correlated with their octanol-water partition coefficients. The regression equations depicting this relationship were used to estimate the extent of past human exposure for the general population of the US to org...

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Bibliographic Details
Published in:Archives of environmental contamination and toxicology 1988-07, Vol.17 (4), p.473-478
Main Authors: TRAVIS, C. C, HATTEMER-FREY, H. A, ARMS, A. D
Format: Article
Language:English
Subjects:
Adipose Tissue - metabolism
Adult
Biological and medical sciences
Chemical and industrial products toxicology. Toxic occupational diseases
Diet
Female
Humans
Insecticides - pharmacokinetics
Medical sciences
Milk, Human - metabolism
Toxicology
Various organic compounds
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Summary:It is demonstrated that the bioaccumulation of organics in human tissues was positively correlated with their octanol-water partition coefficients. The regression equations depicting this relationship were used to estimate the extent of past human exposure for the general population of the US to organics for which measured background tissue concentrations are available. This technique provides an additional tool for evaluating the nature and extent of human exposure to environmental contaminants.
ISSN:0090-4341
1432-0703
DOI:10.1007/BF01055512