Treatment of Acne Vulgaris During Pregnancy and Lactation

Acne vulgaris is a common problem encountered by pregnant and lactating women. Unfortunately, in clinical practice, treatment is often not optimized as a result of the lack of safety data and unified recommendations on the use of the various anti-acne therapies. In this narrative review, current dat...

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Bibliographic Details
Published in:Drugs (New York, N.Y.) N.Y.), 2013-06, Vol.73 (8), p.779-787
Main Authors: Kong, Y. L., Tey, H. L.
Format: Article
Language:English
Subjects:
Acne
Acne Vulgaris - drug therapy
Administration, Oral
Administration, Topical
Androgen Antagonists - administration & dosage
Androgen Antagonists - adverse effects
Anti-Bacterial Agents - administration & dosage
Anti-Bacterial Agents - adverse effects
Antibiotics
Biological and medical sciences
Breastfeeding & lactation
Classification
Dermatology
Female
Humans
Internal Medicine
Lactation - drug effects
Medical sciences
Medicine
Medicine & Public Health
Pharmacology/Toxicology
Pharmacotherapy
Phototherapy - adverse effects
Phototherapy - methods
Pregnancy
Pregnancy Complications - drug therapy
Prescription drugs
Retinoids - administration & dosage
Retinoids - adverse effects
Risk Assessment
Skin involvement in other diseases. Miscellaneous. General aspects
Therapy in Practice
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Summary:Acne vulgaris is a common problem encountered by pregnant and lactating women. Unfortunately, in clinical practice, treatment is often not optimized as a result of the lack of safety data and unified recommendations on the use of the various anti-acne therapies. In this narrative review, current data on their safety is summarized. We recommend the use of topical medications as first-line treatment for acne vulgaris in pregnant and lactating women. These include antibiotics (erythromycin, clindamycin, metronidazole and dapsone), benzoyl peroxide, azelaic acid and salicylic acid. Oral agents and/or light-based therapy may be considered as second-line treatment. The former consists of oral macrolides (erythromycin and azithromycin), cephalexin or zinc compounds. Blue–violet or red light phototherapy may be used as monotherapy or in addition to topical and/or oral therapies. Hormonal therapy, antibiotics consisting of tetracyclines, co-trimoxazole and fluoroquinolones, and both oral and topical retinoids should be avoided.
ISSN:0012-6667
1179-1950
DOI:10.1007/s40265-013-0060-0