Comparing the efficacy of intrauterine lidocaine and paracervical block in decreasing the pain associated with endometrial biopsy: a randomised trial

Purpose Almost 50 % of the patients experience moderate-to-severe pain during endometrial biopsy. The study aimed to examine the effectiveness of intrauterine lidocaine for relieving pain during endometrial biopsy. Methods A randomised trial was conducted in 120 patients undergoing endometrial biops...

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Bibliographic Details
Published in:Archives of gynecology and obstetrics 2014-03, Vol.289 (3), p.609-614
Main Authors: Cengiz, Huseyin, Dağdeviren, Hediye, Kaya, Cihan, Yeşil, Ali, Çaypınar, Sema Süzen
Format: Article
Language:English
Subjects:
Adult
Anesthesia, Obstetrical - adverse effects
Anesthetics, Local - therapeutic use
Biopsy
Biopsy - adverse effects
Effectiveness studies
Endocrinology
Endometrium - pathology
Female
General Gynecology
Gynecology
Human Genetics
Humans
Lidocaine - therapeutic use
Medicine
Medicine & Public Health
Middle Aged
Nerve Block - methods
Obstetrics/Perinatology/Midwifery
Pain
Pain - etiology
Pain - prevention & control
Pain Management - methods
Pain Measurement
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Summary:Purpose Almost 50 % of the patients experience moderate-to-severe pain during endometrial biopsy. The study aimed to examine the effectiveness of intrauterine lidocaine for relieving pain during endometrial biopsy. Methods A randomised trial was conducted in 120 patients undergoing endometrial biopsy. Sixty-seven women were assigned to the paracervical block group and 53 were assigned to the intrauterine lidocaine group. The main outcome measure was pain intensity, measured using the visual analogue scale, during and after the procedure. Results The groups were similar with regard to age, body mass index, gravidity, total number of previous vaginal deliveries, menopausal status, and uterine depth. The pain scores immediately after the procedure were similar in the groups ( p  = 0.079). However, the pain scores 30 min after the procedure were significantly lower in the intrauterine group than in the paracervical group ( p  = 0.0001). Conclusions Compared to paracervical block, intrauterine lidocaine may be the preferred anaesthesia for endometrial biopsy, and it does not cause any serious complications.
ISSN:0932-0067
1432-0711
DOI:10.1007/s00404-013-3036-0