Background parenchymal enhancement on breast MRI: Influence of menstrual cycle and breast composition

Purpose To evaluate the menstrual cycle and breast composition influence on background parenchymal enhancement of breast magnetic resonance imaging (MRI) and to investigate the optimal time for breast MR examinations. Materials and Methods We evaluated the dynamic contrast‐enhanced breast MR images...

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Bibliographic Details
Published in:Journal of magnetic resonance imaging 2014-03, Vol.39 (3), p.526-534
Main Authors: Kang, Seok Seon, Ko, Eun Young, Han, Boo-Kyung, Shin, Jung Hee, Hahn, Soo Yeon, Ko, Eun Sook
Format: Article
Language:English
Subjects:
Adult
Age Factors
breast
Breast - anatomy & histology
Breast - physiology
Cohort Studies
Contrast Media
Female
Humans
Image Interpretation, Computer-Assisted
Magnetic resonance imaging
Magnetic Resonance Imaging - methods
menstrual cycle
Menstrual Cycle - physiology
Middle Aged
parenchymal enhancement
Postmenopause
Premenopause
Prospective Studies
Sensitivity and Specificity
Statistics, Nonparametric
Young Adult
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Summary:Purpose To evaluate the menstrual cycle and breast composition influence on background parenchymal enhancement of breast magnetic resonance imaging (MRI) and to investigate the optimal time for breast MR examinations. Materials and Methods We evaluated the dynamic contrast‐enhanced breast MR images of 238 women who had completed a questionnaire survey about menstrual status. On MRI, the degree of enhancement (DE) of normal parenchyma was measured in the images 2 minutes and 6 minutes after contrast injection. A comparison between premenopausal and postmenopausal women and a separate comparison between dense breasts and fatty breasts were analyzed according to the premenopausal women's menstrual cycle. Results Premenopausal women showed significantly higher DE than the postmenopausal women (P 
ISSN:1053-1807
1522-2586
DOI:10.1002/jmri.24185