Supercontinuum laser based optical characterization of Intralipid® phantoms in the 500-2250 nm range

A supercontinuum laser based double integrating sphere setup in combination with an unscattered transmittance measurement setup was developed and carefully validated for optical characterization of turbid samples in the 500-2250 nm wavelength range. A set of 57 liquid optical phantoms, covering a wi...

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Bibliographic Details
Published in:Optics express 2013-12, Vol.21 (26), p.32450-32467
Main Authors: Aernouts, Ben, Zamora-Rojas, Eduardo, Van Beers, Robbe, Watté, Rodrigo, Wang, Ling, Tsuta, Mizuki, Lammertyn, Jeroen, Saeys, Wouter
Format: Article
Language:English
Subjects:
Algorithms
Emulsions - analysis
Emulsions - chemistry
Lasers
Nanoparticles - chemistry
Nanoparticles - ultrastructure
Nephelometry and Turbidimetry - methods
Phantoms, Imaging
Phospholipids - analysis
Phospholipids - chemistry
Refractometry - methods
Soybean Oil - analysis
Soybean Oil - chemistry
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Summary:A supercontinuum laser based double integrating sphere setup in combination with an unscattered transmittance measurement setup was developed and carefully validated for optical characterization of turbid samples in the 500-2250 nm wavelength range. A set of 57 liquid optical phantoms, covering a wide range of absorption and scattering properties, were prepared and measured at two sample thicknesses. The estimated bulk optical properties matched well for both thicknesses, and with theory and literature, without significant crosstalk between absorption and scattering. Equations were derived for the bulk scattering properties μ(s), μ(s)' and g of Intralipid® 20% which can be used to calculate the bulk scattering properties of intralipid-dilutions in the 500-2250 nm range.
ISSN:1094-4087
1094-4087
DOI:10.1364/oe.21.032450