Assessing Response to Treatment in Non–Small-Cell Lung Cancer: Role of Tumor Volume Evaluated By Computed Tomography

Micro-Abstract To investigate the prognostic value of tumor volume changes, computed tomography examinations from 100 patients with advanced lung cancer were analyzed. Changes in tumor volume were not associated with overall survival. The results suggest that volumetric measurements of tumor size ma...

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Bibliographic Details
Published in:Clinical lung cancer 2014-03, Vol.15 (2), p.103-109
Main Authors: Knollmann, Friedrich D, Kumthekar, Rohan, Fetzer, David, Socinski, Mark A
Format: Article
Language:English
Subjects:
Adenocarcinoma - drug therapy
Adenocarcinoma - mortality
Adenocarcinoma - pathology
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Carcinoma
Carcinoma, Non-Small-Cell Lung - drug therapy
Carcinoma, Non-Small-Cell Lung - mortality
Carcinoma, Non-Small-Cell Lung - pathology
Carcinoma, Squamous Cell - drug therapy
Carcinoma, Squamous Cell - mortality
Carcinoma, Squamous Cell - pathology
Follow-Up Studies
Health Insurance Portability and Accountability Act
Hematology, Oncology and Palliative Medicine
Humans
Imaging
Lung Neoplasms - drug therapy
Lung Neoplasms - mortality
Lung Neoplasms - pathology
Neoplasm Staging
Outcome
Prognosis
Pulmonary/Respiratory
Retrospective Studies
Survival
Survival Rate
Tomography, X-Ray Computed - methods
Tumor Burden
United States
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Description
Summary:Micro-Abstract To investigate the prognostic value of tumor volume changes, computed tomography examinations from 100 patients with advanced lung cancer were analyzed. Changes in tumor volume were not associated with overall survival. The results suggest that volumetric measurements of tumor size may not predict survival with sufficient accuracy to use it as a surrogate marker of treatment success in individual patients.
ISSN:1525-7304
1938-0690
DOI:10.1016/j.cllc.2013.11.001