Strategies to reduce long-term postchemoradiation dysphagia in patients with head and neck cancer: An evidence-based review

Background Swallowing dysfunction following chemoradiation for head and neck cancer is a major cause of morbidity and reduced quality of life. This review discusses 3 strategies that may improve posttreatment swallowing function. Methods The literature was assessed by a multiauthor team that produce...

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Published in:Head & neck 2014-03, Vol.36 (3), p.431-443
Main Authors: Paleri, Vinidh, Roe, Justin W. G., Strojan, Primož, Corry, June, Grégoire, Vincent, Hamoir, Marc, Eisbruch, Avraham, Mendenhall, William M., Silver, Carl E., Rinaldo, Alessandra, Takes, Robert P., Ferlito, Alfio
Format: Article
Language:English
Subjects:
chemoradiation
Chemoradiotherapy
Deglutition Disorders - prevention & control
Deglutition Disorders - rehabilitation
dysphagia
Enteral Nutrition
Exercise Therapy - methods
Head and Neck Neoplasms - therapy
Humans
IMRT
Radiotherapy Dosage
Radiotherapy, Intensity-Modulated
swallowing exercise
Treatment Outcome
tube feeding
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Summary:Background Swallowing dysfunction following chemoradiation for head and neck cancer is a major cause of morbidity and reduced quality of life. This review discusses 3 strategies that may improve posttreatment swallowing function. Methods The literature was assessed by a multiauthor team that produced evidence‐based recommendations. Results (1) Prospective and randomized studies with small cohorts show a trend toward benefits for a preventative exercise program addressing oral and pharyngeal structures. (2) Prospective and retrospective data indicate that better swallowing outcomes are likely when nasogastric tubes are used in preference to gastrostomy tubes to supplement enteral nutrition during chemoradiation. (3) Emerging prospective data with mature results on small cohorts support the hypothesis that radiation dose restriction to swallowing structures using intensity‐modulated radiation therapy techniques leads to better swallow outcomes. Conclusions This study discusses 3 strategies for improving swallow‐related outcomes in patients undergoing chemoradiation for head and neck cancer and identifies areas for future research. © 2013 Wiley Periodicals, Inc. Head Neck 36: 431–443, 2014
ISSN:1043-3074
1097-0347
DOI:10.1002/hed.23251